Divarasib Outperforms First-Gen Competitors in Pretreated KRAS G12C NSCLC

Genentech’s next-generation KRAS G12C inhibitor, divarasib, demonstrated superior survival outcomes over sotorasib and adagrasib in a head-to-head study, maintaining a manageable and consistent safety profile Topline data were announced from a head-to-head phase 3 trial evaluating divarasib vs first generation...

Divarasib Outperforms First-Generation KRAS G12C Inhibitors in Phase III NSCLC Trial

Divarasib, an investigational next-generation KRAS G12C inhibitor, demonstrated statistically significant and clinically meaningful improvements in progression-free survival (PFS) and overall survival (OS) compared with approved first-generation KRAS G12C inhibitors sotorasib (Lumakras) and adagrasib (Krazati) in patients with previously treated, advanced...

Genentech’s Divarasib Outperforms Approved KRAS G12C Inhibitors in Phase III NSCLC Trial

Genentech’s Divarasib Outperforms Approved KRAS G12C Inhibitors in Phase III NSCLC Trial Author : alison doe | Published On : 06 Jul 2026 Genentech Divarasib Phase III Trial has delivered encouraging results after the company announced positive findings from its...

Divarasib Improves Survival Vs Approved KRAS G12C Inhibitors in NSCLC

Divarasib, an oral next-generation KRAS G12C inhibitor, improved progression-free survival (PFS) and overall survival (OS) vs the approved first-generation KRAS G12C inhibitors sotorasib (Lumakras) and adagrasib (Krazati) in patients with previously treated KRAS G12C-mutated advanced or metastatic non–small cell lung...

Roche Reports Positive Phase 3 Results for Divarasib in Previously Treated KRAS G12C NSCLC

Divarasib in KRAS G12C NSCLC improved PFS and OS versus approved KRAS inhibitors in the phase 3 KRASCENDO-1 trial Roche Reports Positive Phase 3 Results for Divarasib in Previously Treated KRAS G12C NSCLC Roche has reported positive top-line results from...

Roche Reports Positive Phase 3 Results for Divarasib in Previously Treated KRAS G12C NSCLC

Roche Reports Positive Phase 3 Results for Divarasib in Previously Treated KRAS G12C NSCLC Roche has reported positive top-line results from KRASCENDO-1, a phase 3 study of divarasib in previously treated KRAS G12C-mutant advanced or metastatic non-small-cell lung cancer. The...

Roche's Divarasib Outperforms First-Generation KRAS G12C Inhibitors in Phase 3 Lung Cancer Trial

Roche's Divarasib Outperforms First-Generation KRAS G12C Inhibitors in Phase 3 Lung Cancer Trial - Clinical Trials Roche has announced positive topline results from its Phase 3 Krascendo 1 study, demonstrating that its investigational next-generation KRAS G12C inhibitor, divarasib, significantly outperformed...

Roche Reports Positive Clinical Trial Results for Divarasib in KRAS G12C-Mutated Lung Cancer

Swiss pharmaceutical company Roche has announced promising clinical trial data for its investigational drug, divarasib. The study evaluated the efficacy of the KRAS G12C inhibitor in patients with non-small cell lung cancer (NSCLC) who have previously undergone standard treatments, marking...

Genentech’s Divarasib Delivers Phase III Survival Benefit in KRAS G12C Non-Small Cell Lung Cancer

Genentech’s Divarasib Delivers Phase III Survival Benefit in KRAS G12C Non-Small Cell Lung Cancer -Genentech, a member of the Roche Group (SIX: RO, ROP; OTCQX: RHHBY), announced positive results from the Phase III Krascendo 1 study evaluating divarasib, an investigational...